

89
19.- DUCHARME F M, LEMIRE C, NOYA F J, DAVIS G
M, ALOS N, LEBLOND H, et al. Preemptive use of
high-dose fluticasone for virus-induced wheezing in
young children. N Engl J Med 2009; 360: 339-53.
20.- BISGAARD H, ZIELEN S, GARCÍA-GARCÍA M L,
JOHNSTON S, GILLES L, MENTEN J, et al. Monte-
lukast reduces asthma exacerbations in 2 to 5 year old
children with intermittent asthma. Am J Respir Crit Care
Med 2005; 171: 315-22.
21.- ROBERTSON C, PRICE D, HENRY R, MELLIS C,
GLASGOW N, FITZGERALD D, et al. Short course
montelukast for intermittent asthma in children. Am J
Respir Crit Care Med 2007; 175: 323-9.
22.- BIRKEN C S, PARKIN P C, MACARTHUR C. Asthma
severity scores for preschoolers displayed weaknesses
in reliability, validity, and responsiveness. J Clin Epide-
miol 2004; 57: 1177-81.
23.- CHALUT D S, DUCHARME F M, DAVIS G M. The
Preschool Respiratory Assessment Measure (PRAM):
A responsive index of acute asthma severity. J Pediatr
2000; 137: 762-8.
24.- REDDEL H K, TAYLOR D R, BATEMAN E D, BOU-
LET L P, BOUSHEY H A, BUSSE WW, et al. An offi-
cial American Thoracic Society/European Respiratory
Society statement: asthma control and exacerbations:
standardizing endpoints for clinical asthma trials and
clinical practice. Am J Crit Care Med 2009; 180: 59-99.
25.- BEKHOF J, REIMINK R, BRAND P L. Systematic
review: Insufficient validation of clinical scores for
the assessment of acute dyspnea in wheezing children.
Paediatr Respir Rev 2014; 15: 98-112.
26.- RALSTON M, HAZINSKI M F, ZARITSKY A L,
SCHEXNAYDER S M, KLEINMAN M E. Pediatric
Advance Life Support Course Guide. Dallas, TX: Ame-
rican Heart Association, 2006.
27.- CARROLLW, LENNEYW. Drug therapy in the mana-
gement of acute asthma. Arch Dis Child Educ Pract Ed
2007; 92 (3): ep82-6.
28.- CASTRO-RODRÍGUEZ J A, RODRIGO G J. Beta-
agonists through metered-dose inhaler with valved
holding chamber
versus
nebulizer for acute exacerbation
of wheezing or asthma in children under 5 years of age:
a systematic review with meta-analysis. J Pediatr 2004;
145: 172-7.
29.- DOUGLAS G, HIGGINS B, BARNES N, BOYTER
A, BURGE S, CATES C, et al. British Guideline on
the Management of Asthma. Thorax 2008; 63 Suppl 4:
1-121.
30.- CAMARGO C A JR, RACHELEFSKY, G, SCHATZ
M. Managing asthma exacerbations in the emergency
department: summary of the National Asthma Education
and Prevention Program Expert Panel Report 3 guide-
lines for the management of asthma exacerbations. J
Emerg Med 2009; 37 (2 Suppl): S6-S17.
31.- ORTIZ-ÁLVAREZ O, MIKROGIANAKIS A. Canadian
Paediatric Society. Acute Care Committee. Managing
the paediatric patient with an acute asthma exacerbation.
Paediatr Child Health 2012; 17: 251-62.
32.- PEDERSEN S E, HURD S S, LEMANSKE R F JR,
BECKER A, ZAR H J, SLY P D, et al. Global Initiative
for Asthma. Global Strategy for the Diagnosis and Ma-
nagement of Asthma in Children 5 Years and Younger.
Pediatr Pulmonol 2011; 46: 1-17.
33.- PAPO M C, FRANK J, THOMPSON A E. A prospecti-
ve, randomized study of continuous
versus
intermittent
nebulized albuterol for severe status asthmaticus in
children. Crit Care Med 1993; 21: 1479-86.
34.- ZORC J J, PUSIC M V, OGBORN C J, LEBET R,
DUGGAN A K. Ipratropium bromide added to asthma
treatment in the pediatric emergency department. Pedia-
trics 1999; 103: 748-52.
35.- PLOTNICK L H, DUCHARME F M. Combined
inhaled anticholinergics and beta 2-agonists for
initial treatment of acute asthma in children. Cochra-
ne Database Syst Rev 2000; (4): CD000060. doi:
10.1002/14651858.
36.- RODRIGO G J, CASTRO-RODRÍGUEZ J A. Anticho-
linergics in the treatment of children and adults with
acute asthma: A systematic review with meta-analysis.
Thorax 2005; 60: 740-6.
37.- GRIFFITHS B I, DUCHARME F M. Combined inha-
led anticholinergics and short-acting beta 2-agonists
for initial treatment of acute asthma in children. Co-
chrane Database Syst Rev 2013; (8): CD000060. doi:
10.1002/14651858.
38.- SMITH M, IQBAL S, ELLIOT T M, EVERARD M,
ROWE B H. Corticosteroids for hospitalized children
with acute asthma. Cochrane Database Syst Rev 2003;
(2): CD002886.
39.- ROWE B H, SPOONER C, DUCHARME F M,
BRETZLAFF J A, BOTA G W, et al. Early emergency
department treatment of acute asthma with systemic
corticosteroids. Cochrane Database Syst Rev 2001; (1):
CD002178.
40.- OOMMEN A, LAMBERT P C, GRIGG J. Ef cacy of
a short course of parent-initiated oral prednisolone for
viral wheeze in children aged 1-5 years: Randomized
controlled trial. Lancet 2003; 362: 1433-8.
41.- PANICKAR J, LAKHANPAUL M, LAMBERT P C,
KENIA P, STEPHENSON T, SMYTH A, et al. Oral
prednisolone for preschool children with acute virus-
induced wheezing. N Engl J Med 2009; 360: 329-38.
42.- BECKER J M, ARORAA, SCARFONE R J, SPECTOR
N D, FONTANA-PENN M E, GRACELY E, et al. Oral
versus
intravenous corticosteroids in children hospita-
lized with asthma. J Allergy Clin Immunol 1999; 103:
586-90.
43.- SCARFONE R J, LOISELLE J M, WILEY J F 2ND,
DECKER J M, HENRETIG F M, JOFFE M D. Ne-
bulized dexamethasone
versus
oral prednisone in the
emergency treatment of asthmatic children. Ann Emerg
Med 1995; 26: 480-6.
Consenso chileno SER-SOCHINEP para el manejo del asma en el preescolar
Rev Chil Enf Respir 2014; 30: 81-90